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Structure and Mechanism of Assembly Line Polyketide Synthases

Assembly line polyketide synthases (PKSs) are remarkable biosynthetic machines with considerable potential for structure-based engineering. Several types of protein-protein interactions, both within and between PKS modules, play important roles in the catalytic cycle of a multimodular PKS. Additiona...

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Bibliographic Details
Published in:Curr Opin Struct Biol
Main Authors: Robbins, Thomas, Liu, Yu-Chen, Cane, David E., Khosla, Chaitan
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5136517/
https://ncbi.nlm.nih.gov/pubmed/27266330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2016.05.009
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