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A Turnstile Mechanism for the Controlled Growth of Biosynthetic Intermediates on Assembly Line Polyketide Synthases

[Image: see text] Vectorial polyketide biosynthesis on an assembly line polyketide synthase is the most distinctive property of this family of biological machines, while providing the key conceptual tool for the bioinformatic decoding of new antibiotic pathways. We now show that the action of the en...

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Detaylı Bibliyografya
Yayımlandı:ACS Cent Sci
Asıl Yazarlar: Lowry, Brian, Li, Xiuyuan, Robbins, Thomas, Cane, David E., Khosla, Chaitan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2016
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731828/
https://ncbi.nlm.nih.gov/pubmed/26878060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.5b00321
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