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A Turnstile Mechanism for the Controlled Growth of Biosynthetic Intermediates on Assembly Line Polyketide Synthases

[Image: see text] Vectorial polyketide biosynthesis on an assembly line polyketide synthase is the most distinctive property of this family of biological machines, while providing the key conceptual tool for the bioinformatic decoding of new antibiotic pathways. We now show that the action of the en...

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Bibliografski detalji
Izdano u:ACS Cent Sci
Glavni autori: Lowry, Brian, Li, Xiuyuan, Robbins, Thomas, Cane, David E., Khosla, Chaitan
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2016
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731828/
https://ncbi.nlm.nih.gov/pubmed/26878060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.5b00321
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