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EXTENDER UNIT AND ACYL CARRIER PROTEIN SPECIFICITY OF KETOSYNTHASE DOMAINS OF THE 6-DEOXYERYTHRONOLIDE B SYNTHASE

Polyketide synthases (PKSs) catalyze the production of numerous biologically important natural products via repeated decarboxylative condensation reactions. Modular PKSs, such as the 6-deoxyerythronolide B synthase (DEBS), consist of multiple catalytic modules, each containing a unique set of covale...

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Bibliographische Detailangaben
Hauptverfasser: Chen, Alice Y., Schnarr, Nathan A., Kim, Chu-Young, Cane, David E., Khosla, Chaitan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532788/
https://ncbi.nlm.nih.gov/pubmed/16506788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja058093d
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