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Mechanism based protein cross-linking of domains from the 6-deoxyerythronolide B synthase

The critical role of protein-protein interactions in the chemistry of polyketide synthases is well established. However, the transient and weak nature of these interactions, in particular those involving the acyl carrier protein (ACP), has hindered efforts to structurally characterize these interact...

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Main Authors: Kapur, Shiven, Worthington, Andrew, Tang, Yinyan, Cane, David E., Burkart, Michael D., Khosla, Chaitan
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430738/
https://ncbi.nlm.nih.gov/pubmed/18243693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.01.073
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