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Mechanism based protein cross-linking of domains from the 6-deoxyerythronolide B synthase

The critical role of protein-protein interactions in the chemistry of polyketide synthases is well established. However, the transient and weak nature of these interactions, in particular those involving the acyl carrier protein (ACP), has hindered efforts to structurally characterize these interact...

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Détails bibliographiques
Auteurs principaux: Kapur, Shiven, Worthington, Andrew, Tang, Yinyan, Cane, David E., Burkart, Michael D., Khosla, Chaitan
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430738/
https://ncbi.nlm.nih.gov/pubmed/18243693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.01.073
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