Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects

Glucocorticoids (GCs) are the most commonly used antiinflammatory and immunosuppressive drugs. Their outstanding therapeutic effects, however, are often accompanied by severe and sometimes irreversible side effects. For this reason, one goal of research in the GC field is the development of new drug...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Schäcke, Heike, Schottelius, Arndt, Döcke, Wolf-Dietrich, Strehlke, Peter, Jaroch, Stefan, Schmees, Norbert, Rehwinkel, Hartmut, Hennekes, Hartwig, Asadullah, Khusru
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2004
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC314167/
https://ncbi.nlm.nih.gov/pubmed/14694204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0300372101
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires