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The glucocorticoid RU24858 does not distinguish between transrepression and transactivation in primary human eosinophils

<p>Abstract</p> <p>Background</p> <p>Glucocorticoids are used to treat chronic inflammatory diseases such as asthma. Induction of eosinophil apoptosis is considered to be one of the main mechanisms behind the anti-asthmatic effect of glucocorticoids. Glucocorticoid binding to its receptor (GR) can h...

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Principais autores: Zhang Xianzhi, Hasala Hannele, Moilanen Eeva, Janka-Junttila Mirkka, Adcock Ian, Kankaanranta Hannu
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2006-07-01
Colecção:Journal of Inflammation
Acesso em linha:http://www.journal-inflammation.com/content/3/1/10
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