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Down-Regulation of Tristetraprolin Expression Results in Enhanced IL-12 and MIP-2 Production and Reduced MIP-3α Synthesis in Activated Macrophages

In inflammation, the post-transcriptional regulation of transiently expressed genes provides a potential therapeutic target. Tristetraprolin (TTP) is of the factors regulating decay of cytokine mRNAs. The aim of the present study was to identify cytokines whose expression is regulated by TTP. We est...

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Principais autores: Ulla Jalonen, Riina Nieminen, Katriina Vuolteenaho, Hannu Kankaanranta, Eeva Moilanen
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2006-01-01
Colecção:Mediators of Inflammation
Acesso em linha:http://dx.doi.org/10.1155/MI/2006/40691
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