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Prion protein biosynthesis and its emerging role in neurodegeneration
Various fatal neurodegenerative disorders are caused by altered metabolism of the prion protein (PrP). These diseases are typically transmissible by an unusual ‘protein-only’ mechanism in which a misfolded isomer, PrP(Sc), confers its aberrant conformation onto normal cellular PrP. An impressive ran...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3132587/ https://ncbi.nlm.nih.gov/pubmed/19447626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2009.03.001 |
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