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Signal sequence insufficiency contributes to neurodegeneration caused by transmembrane prion protein
Protein translocation into the endoplasmic reticulum is mediated by signal sequences that vary widely in primary structure. In vitro studies suggest that such signal sequence variations may correspond to subtly different functional properties. Whether comparable functional differences exist in vivo...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Rockefeller University Press
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2828915/ https://ncbi.nlm.nih.gov/pubmed/20156965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200911115 |
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