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Trifluoperazine Regulation of Calmodulin Binding to Fas: A Computational Study
Death-inducing signaling complex (DISC) formation is a critical step in Fas-mediated signaling for apoptosis. Previous experiments have demonstrated that the calmodulin (CaM) antagonist, trifluoperazine (TFP) regulates CaM-Fas binding and affects Fas-mediated DISC formation. In this study, we invest...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3132223/ https://ncbi.nlm.nih.gov/pubmed/21656570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.23081 |
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