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Fas Binding to Calmodulin Regulates Apoptosis in Osteoclasts
Promotion of osteoclast apoptosis is one therapeutic approach to osteoporosis. Calmodulin, the major intracellular Ca(2+) receptor, modulates both osteoclastogenesis and bone resorption. The calmodulin antagonist, trifluoperazine, rescues bone loss in ovariectomized mice (Zhang, L., Feng, X., and Mc...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1351015/ https://ncbi.nlm.nih.gov/pubmed/15965236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M500710200 |
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