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The Combination of Calmodulin Antagonists and Interferon-γ Induces Apoptosis through Caspase-Dependent and -Independent Pathways in Cholangiocarcinoma Cells

Calmodulin (CaM) antagonists have been shown to inhibit tumor cell invasion and metastasis and to induce apoptosis in various tumor models, but the molecular mechanism of CaM antagonist-mediated apoptosis is poorly understood. Here, we demonstrate that interferon (IFN)-γ induces susceptibility to Ca...

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Detalhes bibliográficos
Main Authors: Ahn, Eun-Young, Pan, George, Oh, Jae Hwan, Tytler, Ewan M., McDonald, Jay M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892439/
https://ncbi.nlm.nih.gov/pubmed/14578204
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