Calmodulin Mediates Fas-induced FADD-independent Survival Signaling in Pancreatic Cancer Cells via Activation of Src-Extracellular Signal-regulated Kinase (ERK)

Pancreatic cancer remains a devastating malignancy with a poor prognosis and is largely resistant to current therapies. To understand the resistance of pancreatic tumors to Fas death receptor-induced apoptosis, we investigated the molecular mechanisms of Fas-activated survival signaling in pancreati...

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Detalhes bibliográficos
Main Authors: Yuan, Kaiyu, Jing, Gu, Chen, Jianfeng, Liu, Hui, Zhang, Kui, Li, Yuebin, Wu, Hui, McDonald, Jay M., Chen, Yabing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137053/
https://ncbi.nlm.nih.gov/pubmed/21613217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.202804
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