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Conformation and Free Energy Analyses of the Complex of Calcium-Bound Calmodulin and the Fas Death Domain

Previous studies have demonstrated a calcium-dependent interaction of calmodulin (CaM) and Fas that is regulated during Fas-induced apoptosis in several cell lines, including cholangiocarcinoma, Jurkat cells, and osteoclasts. The binding of CaM and Fas has been identified on residues 231–254 of Fas;...

詳細記述

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書誌詳細
主要な著者: Suever, Jonathan D., Chen, Yabing, McDonald, Jay M., Song, Yuhua
フォーマット: Artigo
言語:Inglês
出版事項: The Biophysical Society 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2599819/
https://ncbi.nlm.nih.gov/pubmed/18820240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.130542
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