Characterization of Calmodulin–Fas Death Domain Interaction: An Integrated Experimental and Computational Study

[Image: see text] The Fas death receptor-activated death-inducing signaling complex (DISC) regulates apoptosis in many normal and cancer cells. Qualitative biochemical experiments demonstrate that calmodulin (CaM) binds to the death domain of Fas. The interaction between CaM and Fas regulates Fas-me...

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Detalhes bibliográficos
Main Authors: Fancy, Romone M., Wang, Lingyun, Napier, Tiara, Lin, Jiabei, Jing, Gu, Lucius, Aaron L., McDonald, Jay M., Zhou, Tong, Song, Yuhua
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007977/
https://ncbi.nlm.nih.gov/pubmed/24702583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500228h
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