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Characterization of Calmodulin–Fas Death Domain Interaction: An Integrated Experimental and Computational Study

[Image: see text] The Fas death receptor-activated death-inducing signaling complex (DISC) regulates apoptosis in many normal and cancer cells. Qualitative biochemical experiments demonstrate that calmodulin (CaM) binds to the death domain of Fas. The interaction between CaM and Fas regulates Fas-me...

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Détails bibliographiques
Auteurs principaux: Fancy, Romone M., Wang, Lingyun, Napier, Tiara, Lin, Jiabei, Jing, Gu, Lucius, Aaron L., McDonald, Jay M., Zhou, Tong, Song, Yuhua
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2014
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007977/
https://ncbi.nlm.nih.gov/pubmed/24702583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500228h
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