Characterization of the Interactions between Calmodulin and Death Receptor 5 in Triple-negative and Estrogen Receptor-positive Breast Cancer Cells: AN INTEGRATED EXPERIMENTAL AND COMPUTATIONAL STUDY

Activation of death receptor-5 (DR5) leads to the formation of death inducing signaling complex (DISC) for apoptotic signaling. Targeting DR5 to induce breast cancer apoptosis is a promising strategy to circumvent drug resistance and present a target for breast cancer treatment. Calmodulin (CaM) has...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Fancy, Romone M., Wang, Lingyun, Zeng, Qinghua, Wang, Hong, Zhou, Tong, Buchsbaum, Donald J., Song, Yuhua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933462/
https://ncbi.nlm.nih.gov/pubmed/27129269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.727727
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