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Structural and Biophysical Characterization of the Interactions between the Death Domain of Fas Receptor and Calmodulin
The extrinsic apoptotic pathway is initiated by cell surface death receptors such as Fas. Engagement of Fas by Fas ligand triggers a conformational change that allows Fas to interact with adaptor protein Fas-associated death domain (FADD) via the death domain, which recruits downstream signaling pro...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3724645/ https://ncbi.nlm.nih.gov/pubmed/23760276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.471821 |
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