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Structural and Biophysical Characterization of the Interactions between the Death Domain of Fas Receptor and Calmodulin

The extrinsic apoptotic pathway is initiated by cell surface death receptors such as Fas. Engagement of Fas by Fas ligand triggers a conformational change that allows Fas to interact with adaptor protein Fas-associated death domain (FADD) via the death domain, which recruits downstream signaling pro...

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Hlavní autoři: Fernandez, Timothy F., Samal, Alexandra B., Bedwell, Gregory J., Chen, Yabing, Saad, Jamil S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724645/
https://ncbi.nlm.nih.gov/pubmed/23760276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.471821
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