Regulation of Pyruvate Dehydrogenase Kinase 4 (PDK4) by CCAAT/Enhancer-binding Protein β (C/EBPβ)

The conversion of pyruvate to acetyl-CoA in mitochondria is catalyzed by the pyruvate dehydrogenase complex (PDC). Activity of PDC is inhibited by phosphorylation via the pyruvate dehydrogenase kinases (PDKs). Here, we examined the regulation of Pdk4 gene expression by the CCAAT/enhancer-binding pro...

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Autori principali: Attia, Ramy R., Sharma, Pragya, Janssen, Rachel C., Friedman, Jacob E., Deng, Xiong, Lee, Jae Seung, Elam, Marshall B., Cook, George A., Park, Edwards A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
Soggetti:
Gene Regulation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129161/
https://ncbi.nlm.nih.gov/pubmed/21586575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.246389
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