Regulation of Pyruvate Dehydrogenase Kinase 4 (PDK4) by CCAAT/Enhancer-binding Protein β (C/EBPβ)

The conversion of pyruvate to acetyl-CoA in mitochondria is catalyzed by the pyruvate dehydrogenase complex (PDC). Activity of PDC is inhibited by phosphorylation via the pyruvate dehydrogenase kinases (PDKs). Here, we examined the regulation of Pdk4 gene expression by the CCAAT/enhancer-binding pro...

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Main Authors: Attia, Ramy R., Sharma, Pragya, Janssen, Rachel C., Friedman, Jacob E., Deng, Xiong, Lee, Jae Seung, Elam, Marshall B., Cook, George A., Park, Edwards A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Gene Regulation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129161/
https://ncbi.nlm.nih.gov/pubmed/21586575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.246389
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