Regulation of Pyruvate Dehydrogenase Kinase 4 (PDK4) by CCAAT/Enhancer-binding Protein β (C/EBPβ)

The conversion of pyruvate to acetyl-CoA in mitochondria is catalyzed by the pyruvate dehydrogenase complex (PDC). Activity of PDC is inhibited by phosphorylation via the pyruvate dehydrogenase kinases (PDKs). Here, we examined the regulation of Pdk4 gene expression by the CCAAT/enhancer-binding pro...

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Détails bibliographiques
Auteurs principaux: Attia, Ramy R., Sharma, Pragya, Janssen, Rachel C., Friedman, Jacob E., Deng, Xiong, Lee, Jae Seung, Elam, Marshall B., Cook, George A., Park, Edwards A.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Gene Regulation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129161/
https://ncbi.nlm.nih.gov/pubmed/21586575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.246389
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