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Regulation of Pyruvate Dehydrogenase Kinase 4 (PDK4) by CCAAT/Enhancer-binding Protein β (C/EBPβ)

The conversion of pyruvate to acetyl-CoA in mitochondria is catalyzed by the pyruvate dehydrogenase complex (PDC). Activity of PDC is inhibited by phosphorylation via the pyruvate dehydrogenase kinases (PDKs). Here, we examined the regulation of Pdk4 gene expression by the CCAAT/enhancer-binding pro...

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Detalhes bibliográficos
Main Authors: Attia, Ramy R., Sharma, Pragya, Janssen, Rachel C., Friedman, Jacob E., Deng, Xiong, Lee, Jae Seung, Elam, Marshall B., Cook, George A., Park, Edwards A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129161/
https://ncbi.nlm.nih.gov/pubmed/21586575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.246389
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