Regulation of Pyruvate Dehydrogenase Kinase 4 (PDK4) by CCAAT/Enhancer-binding Protein β (C/EBPβ)

The conversion of pyruvate to acetyl-CoA in mitochondria is catalyzed by the pyruvate dehydrogenase complex (PDC). Activity of PDC is inhibited by phosphorylation via the pyruvate dehydrogenase kinases (PDKs). Here, we examined the regulation of Pdk4 gene expression by the CCAAT/enhancer-binding pro...

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Bibliografiske detaljer
Main Authors: Attia, Ramy R., Sharma, Pragya, Janssen, Rachel C., Friedman, Jacob E., Deng, Xiong, Lee, Jae Seung, Elam, Marshall B., Cook, George A., Park, Edwards A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Gene Regulation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129161/
https://ncbi.nlm.nih.gov/pubmed/21586575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.246389
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