Defining Structural and Functional Dimensions of the Extracellular Thyrotropin Receptor Region

The extracellular region of the thyrotropin receptor (TSHR) can be subdivided into the leucine-rich repeat domain (LRRD) and the hinge region. Both the LRRD and the hinge region interact with thyrotropin (TSH) or autoantibodies. Structural data for the TSHR LRRD were previously determined by crystal...

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Hlavní autoři: Kleinau, Gunnar, Mueller, Sandra, Jaeschke, Holger, Grzesik, Paul, Neumann, Susanne, Diehl, Anne, Paschke, Ralf, Krause, Gerd
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121406/
https://ncbi.nlm.nih.gov/pubmed/21525003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.211193
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