Defining Structural and Functional Dimensions of the Extracellular Thyrotropin Receptor Region

The extracellular region of the thyrotropin receptor (TSHR) can be subdivided into the leucine-rich repeat domain (LRRD) and the hinge region. Both the LRRD and the hinge region interact with thyrotropin (TSH) or autoantibodies. Structural data for the TSHR LRRD were previously determined by crystal...

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Detalhes bibliográficos
Main Authors: Kleinau, Gunnar, Mueller, Sandra, Jaeschke, Holger, Grzesik, Paul, Neumann, Susanne, Diehl, Anne, Paschke, Ralf, Krause, Gerd
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121406/
https://ncbi.nlm.nih.gov/pubmed/21525003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.211193
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