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Evidence for cooperative signal triggering at the extracellular loops of the TSH receptor
The mechanisms governing transition of the thyroid stimulating hormone (TSH) receptor (TSHR) from basal to active conformations are poorly understood. Considering that constitutively activating mutations (CAMs) and inactivating mutations in each of the extracellular loops (ECLs) trigger only partial...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The Federation of American Societies for Experimental Biology
2008
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2493456/ https://ncbi.nlm.nih.gov/pubmed/18381815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.07-104711 |
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