Defining Structural and Functional Dimensions of the Extracellular Thyrotropin Receptor Region

The extracellular region of the thyrotropin receptor (TSHR) can be subdivided into the leucine-rich repeat domain (LRRD) and the hinge region. Both the LRRD and the hinge region interact with thyrotropin (TSH) or autoantibodies. Structural data for the TSHR LRRD were previously determined by crystal...

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Détails bibliographiques
Auteurs principaux: Kleinau, Gunnar, Mueller, Sandra, Jaeschke, Holger, Grzesik, Paul, Neumann, Susanne, Diehl, Anne, Paschke, Ralf, Krause, Gerd
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Signal Transduction
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121406/
https://ncbi.nlm.nih.gov/pubmed/21525003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.211193
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