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Defining Structural and Functional Dimensions of the Extracellular Thyrotropin Receptor Region
The extracellular region of the thyrotropin receptor (TSHR) can be subdivided into the leucine-rich repeat domain (LRRD) and the hinge region. Both the LRRD and the hinge region interact with thyrotropin (TSH) or autoantibodies. Structural data for the TSHR LRRD were previously determined by crystal...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Biochemistry and Molecular Biology
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3121406/ https://ncbi.nlm.nih.gov/pubmed/21525003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.211193 |
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