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Extended and Structurally Supported Insights into Extracellular Hormone Binding, Signal Transduction and Organization of the Thyrotropin Receptor

The hormone thyrotropin (TSH) and its receptor (TSHR) are crucial for the growth and function of the thyroid gland. The TSHR is evolutionary linked with the receptors of follitropin (FSHR) and lutropin/choriogonadotropin (LHR) and their sequences and structures are similar. The extracellular region...

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Detalhes bibliográficos
Main Authors: Krause, Gerd, Kreuchwig, Annika, Kleinau, Gunnar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531376/
https://ncbi.nlm.nih.gov/pubmed/23300822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052920
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