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Extended and Structurally Supported Insights into Extracellular Hormone Binding, Signal Transduction and Organization of the Thyrotropin Receptor

The hormone thyrotropin (TSH) and its receptor (TSHR) are crucial for the growth and function of the thyroid gland. The TSHR is evolutionary linked with the receptors of follitropin (FSHR) and lutropin/choriogonadotropin (LHR) and their sequences and structures are similar. The extracellular region...

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Библиографические подробности
Главные авторы: Krause, Gerd, Kreuchwig, Annika, Kleinau, Gunnar
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531376/
https://ncbi.nlm.nih.gov/pubmed/23300822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052920
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