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Extended and Structurally Supported Insights into Extracellular Hormone Binding, Signal Transduction and Organization of the Thyrotropin Receptor

The hormone thyrotropin (TSH) and its receptor (TSHR) are crucial for the growth and function of the thyroid gland. The TSHR is evolutionary linked with the receptors of follitropin (FSHR) and lutropin/choriogonadotropin (LHR) and their sequences and structures are similar. The extracellular region...

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Autors principals: Krause, Gerd, Kreuchwig, Annika, Kleinau, Gunnar
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531376/
https://ncbi.nlm.nih.gov/pubmed/23300822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052920
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