From Molecular Details of the Interplay between Transmembrane Helices of the Thyrotropin Receptor to General Aspects of Signal Transduction in Family A G-protein-coupled Receptors (GPCRs)

Transmembrane helices (TMHs) 5 and 6 are known to be important for signal transduction by G-protein-coupled receptors (GPCRs). Our aim was to characterize the interface between TMH5 and TMH6 of the thyrotropin receptor (TSHR) to gain molecular insights into aspects of signal transduction and regulat...

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Detalhes bibliográficos
Main Authors: Kleinau, Gunnar, Hoyer, Inna, Kreuchwig, Annika, Haas, Ann-Karin, Rutz, Claudia, Furkert, Jens, Worth, Catherine L., Krause, Gerd, Schülein, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138303/
https://ncbi.nlm.nih.gov/pubmed/21586576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.196980
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