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Galanin transgenic mice display cognitive and neurochemical deficits characteristic of Alzheimer's disease

Galanin is a neuropeptide with multiple inhibitory actions on neurotransmission and memory. In Alzheimer's disease (AD), increased galanin-containing fibers hyperinnervate cholinergic neurons within the basal forebrain in association with a decline in cognition. We generated transgenic mice (GAL-tg)...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Steiner, Robert A., Hohmann, John G., Holmes, Andrew, Wrenn, Craige C., Cadd, Gary, Juréus, Anders, Clifton, Donald K., Luo, Mulon, Gutshall, Mitchell, Ma, Shuang Y., Mufson, Elliott J., Crawley, Jacqueline N.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31200/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11259657/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.061445598
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