Galanin transgenic mice display cognitive and neurochemical deficits characteristic of Alzheimer's disease

Galanin is a neuropeptide with multiple inhibitory actions on neurotransmission and memory. In Alzheimer's disease (AD), increased galanin-containing fibers hyperinnervate cholinergic neurons within the basal forebrain in association with a decline in cognition. We generated transgenic mice (GAL-tg)...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Steiner, Robert A., Hohmann, John G., Holmes, Andrew, Wrenn, Craige C., Cadd, Gary, Juréus, Anders, Clifton, Donald K., Luo, Mulon, Gutshall, Mitchell, Ma, Shuang Y., Mufson, Elliott J., Crawley, Jacqueline N.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2001
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31200/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11259657/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.061445598
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!