Galanin transgenic mice display cognitive and neurochemical deficits characteristic of Alzheimer's disease

Galanin is a neuropeptide with multiple inhibitory actions on neurotransmission and memory. In Alzheimer's disease (AD), increased galanin-containing fibers hyperinnervate cholinergic neurons within the basal forebrain in association with a decline in cognition. We generated transgenic mice (GAL-tg)...

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Podrobná bibliografie

Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Steiner, Robert A., Hohmann, John G., Holmes, Andrew, Wrenn, Craige C., Cadd, Gary, Juréus, Anders, Clifton, Donald K., Luo, Mulon, Gutshall, Mitchell, Ma, Shuang Y., Mufson, Elliott J., Crawley, Jacqueline N.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 2001
Témata:	Biological Sciences
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31200/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11259657/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.061445598
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