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Transgenic overexpression of galanin in the dorsal root ganglia modulates pain-related behavior

The neuropeptide galanin is expressed in the dorsal root ganglia (DRG) and spinal cord and is thought to be involved in the modulation of pain processing. However, its mechanisms of action are complex and poorly understood, as both facilitatory and inhibitory effects have been described. To understa...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Holmes, Fiona E., Bacon, Andrea, Pope, Robert J. P., Vanderplank, Penny A., Kerr, Niall C. H., Sukumaran, Madhu, Pachnis, Vassilis, Wynick, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2003
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156346/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12721371/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0937087100
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