Galanin transgenic mice display cognitive and neurochemical deficits characteristic of Alzheimer's disease

Galanin is a neuropeptide with multiple inhibitory actions on neurotransmission and memory. In Alzheimer's disease (AD), increased galanin-containing fibers hyperinnervate cholinergic neurons within the basal forebrain in association with a decline in cognition. We generated transgenic mice (GAL-tg)...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Steiner, Robert A., Hohmann, John G., Holmes, Andrew, Wrenn, Craige C., Cadd, Gary, Juréus, Anders, Clifton, Donald K., Luo, Mulon, Gutshall, Mitchell, Ma, Shuang Y., Mufson, Elliott J., Crawley, Jacqueline N.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31200/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11259657/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.061445598
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