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A Linear Model for Transcription Factor Binding Affinity Prediction in Protein Binding Microarrays

Protein binding microarrays (PBM) are a high throughput technology used to characterize protein-DNA binding. The arrays measure a protein's affinity toward thousands of double-stranded DNA sequences at once, producing a comprehensive binding specificity catalog. We present a linear model for pr...

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Hlavní autoři: Annala, Matti, Laurila, Kirsti, Lähdesmäki, Harri, Nykter, Matti
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102690/
https://ncbi.nlm.nih.gov/pubmed/21637853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020059
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