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A Linear Model for Transcription Factor Binding Affinity Prediction in Protein Binding Microarrays

Protein binding microarrays (PBM) are a high throughput technology used to characterize protein-DNA binding. The arrays measure a protein's affinity toward thousands of double-stranded DNA sequences at once, producing a comprehensive binding specificity catalog. We present a linear model for pr...

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Bibliografiske detaljer
Main Authors: Annala, Matti, Laurila, Kirsti, Lähdesmäki, Harri, Nykter, Matti
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102690/
https://ncbi.nlm.nih.gov/pubmed/21637853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020059
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