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Predicting the effects of SNPs on transcription factor binding affinity
MOTIVATION: Genome-wide association studies have revealed that 88% of disease-associated single-nucleotide polymorphisms (SNPs) reside in noncoding regions. However, noncoding SNPs remain understudied, partly because they are challenging to prioritize for experimental validation. To address this def...
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| Pubblicato in: | Bioinformatics |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7999143/ https://ncbi.nlm.nih.gov/pubmed/31373606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz612 |
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