Predicting the effects of SNPs on transcription factor binding affinity

MOTIVATION: Genome-wide association studies have revealed that 88% of disease-associated single-nucleotide polymorphisms (SNPs) reside in noncoding regions. However, noncoding SNPs remain understudied, partly because they are challenging to prioritize for experimental validation. To address this def...

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Bibliografski detalji
Izdano u:Bioinformatics
Glavni autori: Nishizaki, Sierra S, Ng, Natalie, Dong, Shengcheng, Porter, Robert S, Morterud, Cody, Williams, Colten, Asman, Courtney, Switzenberg, Jessica A, Boyle, Alan P
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Original Papers
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7999143/
https://ncbi.nlm.nih.gov/pubmed/31373606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz612
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