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Nucleotides of transcription factor binding sites exert interdependent effects on the binding affinities of transcription factors

We can determine the effects of many possible sequence variations in transcription factor binding sites using microarray binding experiments. Analysis of wild-type and mutant Zif268 (Egr1) zinc fingers bound to microarrays containing all possible central 3 bp triplet binding sites indicates that the...

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Autors principals: Bulyk, Martha L., Johnson, Philip L. F., Church, George M.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC101241/
https://ncbi.nlm.nih.gov/pubmed/11861919
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