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Predicting gene expression in T cell differentiation from histone modifications and transcription factor binding affinities by linear mixture models

BACKGROUND: The differentiation process from stem cells to fully differentiated cell types is controlled by the interplay of chromatin modifications and transcription factor activity. Histone modifications or transcription factors frequently act in a multi-functional manner, with a given DNA motif o...

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Detalhes bibliográficos
Main Authors: Costa, Ivan G, Roider, Helge G, do Rego, Thais G, de Carvalho, Francisco de AT
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044284/
https://ncbi.nlm.nih.gov/pubmed/21342559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-S1-S29
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