Predicting gene expression in T cell differentiation from histone modifications and transcription factor binding affinities by linear mixture models

BACKGROUND: The differentiation process from stem cells to fully differentiated cell types is controlled by the interplay of chromatin modifications and transcription factor activity. Histone modifications or transcription factors frequently act in a multi-functional manner, with a given DNA motif o...

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Hauptverfasser: Costa, Ivan G, Roider, Helge G, do Rego, Thais G, de Carvalho, Francisco de AT
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044284/
https://ncbi.nlm.nih.gov/pubmed/21342559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-S1-S29
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