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Transcription factor binding predicts histone modifications in human cell lines

Gene expression in higher organisms is thought to be regulated by a complex network of transcription factor binding and chromatin modifications, yet the relative importance of these two factors remains a matter of debate. Here, we show that a computational approach allows surprisingly accurate predi...

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Hlavní autoři: Benveniste, Dan, Sonntag, Hans-Joachim, Sanguinetti, Guido, Sproul, Duncan
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169916/
https://ncbi.nlm.nih.gov/pubmed/25187560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1412081111
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