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Statistical Modeling of Transcription Factor Binding Affinities Predicts Regulatory Interactions

Recent experimental and theoretical efforts have highlighted the fact that binding of transcription factors to DNA can be more accurately described by continuous measures of their binding affinities, rather than a discrete description in terms of binding sites. While the binding affinities can be pr...

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Detalhes bibliográficos
Main Authors: Manke, Thomas, Roider, Helge G., Vingron, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266803/
https://ncbi.nlm.nih.gov/pubmed/18369429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000039
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