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Mutational analysis of the propensity for amyloid formation by a globular protein
Acylphosphatase can be converted in vitro, by addition of trifluoroethanol (TFE), into amyloid fibrils of the type observed in a range of human diseases. The propensity to form fibrils has been investigated for a series of mutants of acylphosphatase by monitoring the range of TFE concentrations that...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | EMBO J |
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| Prif Awduron: | , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Nature Publishing Group
2000
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310213/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10747012/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.7.1441 |
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