The protofilament structure of insulin amyloid fibrils
Under solution conditions where the native state is destabilized, the largely helical polypeptide hormone insulin readily aggregates to form amyloid fibrils with a characteristic cross-β structure. However, there is a lack of information relating the 4.8 Å β-strand repeat to the higher order assembl...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2002
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123117/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12093917/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.142459399 |
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