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A computational approach for identifying the chemical factors involved in the glycosaminoglycans-mediated acceleration of amyloid fibril formation.

<h4>Background</h4>Amyloid fibril formation is the hallmark of many human diseases, including Alzheimer's disease, type II diabetes and amyloidosis. Amyloid fibrils deposit in the extracellular space and generally co-localize with the glycosaminoglycans (GAGs) of the basement membrane. GAGs have bee...

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Detaylı Bibliyografya
Asıl Yazarlar: Elodie Monsellier, Matteo Ramazzotti, Niccolò Taddei, Fabrizio Chiti
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2010-06-01
Seri Bilgileri:PLoS ONE
Online Erişim:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20613870/?tool=EBI
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