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Mutational analysis of the propensity for amyloid formation by a globular protein
Acylphosphatase can be converted in vitro, by addition of trifluoroethanol (TFE), into amyloid fibrils of the type observed in a range of human diseases. The propensity to form fibrils has been investigated for a series of mutants of acylphosphatase by monitoring the range of TFE concentrations that...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2000
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC310213/ https://ncbi.nlm.nih.gov/pubmed/10747012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.7.1441 |
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