Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells

Induced pluripotent stem cells (iPSCs) offer immense potential for regenerative medicine and studies of disease and development. Somatic cell reprogramming involves epigenomic reconfiguration, conferring iPSCs with characteristics similar to embryonic stem (ES) cells. However, it remains unknown how...

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Hlavní autoři: Lister, Ryan, Pelizzola, Mattia, Kida, Yasuyuki S., Hawkins, R. David, Nery, Joseph R., Hon, Gary, Antosiewicz-Bourget, Jessica, O'Malley, Ronan, Castanon, Rosa, Klugman, Sarit, Downes, Michael, Yu, Ruth, Stewart, Ron, Ren, Bing, Thomson, James A., Evans, Ronald M., Ecker, Joseph R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100360/
https://ncbi.nlm.nih.gov/pubmed/21289626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09798
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