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Cerebral Organoids Recapitulate Epigenomic Signatures of the Human Fetal Brain

Organoids derived from human pluripotent stem cells recapitulate the early three-dimensional organization of the human brain, but whether they establish the epigenomic and transcriptional programs essential for brain development is unknown. We compared epigenomic and regulatory features in cerebral...

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Bibliografische gegevens
Gepubliceerd in:Cell Rep
Hoofdauteurs: Luo, Chongyuan, Lancaster, Madeline A., Castanon, Rosa, Nery, Joseph R., Knoblich, Juergen A., Ecker, Joseph R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495578/
https://ncbi.nlm.nih.gov/pubmed/28009303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.12.001
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