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Cerebral Organoids Recapitulate Epigenomic Signatures of the Human Fetal Brain
Organoids derived from human pluripotent stem cells recapitulate the early three-dimensional organization of the human brain, but whether they establish the epigenomic and transcriptional programs essential for brain development is unknown. We compared epigenomic and regulatory features in cerebral...
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| Publicado en: | Cell Rep |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5495578/ https://ncbi.nlm.nih.gov/pubmed/28009303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.12.001 |
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