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Cerebral Organoids Recapitulate Epigenomic Signatures of the Human Fetal Brain

Organoids derived from human pluripotent stem cells recapitulate the early three-dimensional organization of the human brain, but whether they establish the epigenomic and transcriptional programs essential for brain development is unknown. We compared epigenomic and regulatory features in cerebral...

詳細記述

保存先:
書誌詳細
出版年:Cell Rep
主要な著者: Luo, Chongyuan, Lancaster, Madeline A., Castanon, Rosa, Nery, Joseph R., Knoblich, Juergen A., Ecker, Joseph R.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495578/
https://ncbi.nlm.nih.gov/pubmed/28009303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.12.001
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