Human cerebral organoids recapitulate gene expression programs of fetal neocortex development

Cerebral organoids—3D cultures of human cerebral tissue derived from pluripotent stem cells—have emerged as models of human cortical development. However, the extent to which in vitro organoid systems recapitulate neural progenitor cell proliferation and neuronal differentiation programs observed in...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Camp, J. Gray, Badsha, Farhath, Florio, Marta, Kanton, Sabina, Gerber, Tobias, Wilsch-Bräuninger, Michaela, Lewitus, Eric, Sykes, Alex, Hevers, Wulf, Lancaster, Madeline, Knoblich, Juergen A., Lachmann, Robert, Pääbo, Svante, Huttner, Wieland B., Treutlein, Barbara
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697386/
https://ncbi.nlm.nih.gov/pubmed/26644564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520760112
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