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A single splice site mutation in human-specific ARHGAP11B causes basal progenitor amplification
The gene ARHGAP11B promotes basal progenitor amplification and is implicated in neocortex expansion. It arose on the human evolutionary lineage by partial duplication of ARHGAP11A, which encodes a Rho guanosine triphosphatase–activating protein (RhoGAP). However, a lack of 55 nucleotides in ARHGAP11...
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| 出版年: | Sci Adv |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Association for the Advancement of Science
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5142801/ https://ncbi.nlm.nih.gov/pubmed/27957544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1601941 |
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