Učitavanje...

A single splice site mutation in human-specific ARHGAP11B causes basal progenitor amplification

The gene ARHGAP11B promotes basal progenitor amplification and is implicated in neocortex expansion. It arose on the human evolutionary lineage by partial duplication of ARHGAP11A, which encodes a Rho guanosine triphosphatase–activating protein (RhoGAP). However, a lack of 55 nucleotides in ARHGAP11...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Sci Adv
Glavni autori: Florio, Marta, Namba, Takashi, Pääbo, Svante, Hiller, Michael, Huttner, Wieland B.
Format: Artigo
Jezik:Inglês
Izdano: American Association for the Advancement of Science 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142801/
https://ncbi.nlm.nih.gov/pubmed/27957544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1601941
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!