Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells

Induced pluripotent stem cells (iPSCs) offer immense potential for regenerative medicine and studies of disease and development. Somatic cell reprogramming involves epigenomic reconfiguration, conferring iPSCs with characteristics similar to embryonic stem (ES) cells. However, it remains unknown how...

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Bibliografische gegevens
Hoofdauteurs: Lister, Ryan, Pelizzola, Mattia, Kida, Yasuyuki S., Hawkins, R. David, Nery, Joseph R., Hon, Gary, Antosiewicz-Bourget, Jessica, O'Malley, Ronan, Castanon, Rosa, Klugman, Sarit, Downes, Michael, Yu, Ruth, Stewart, Ron, Ren, Bing, Thomson, James A., Evans, Ronald M., Ecker, Joseph R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100360/
https://ncbi.nlm.nih.gov/pubmed/21289626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09798
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