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The Protease-activated Receptor-2-specific Agonists 2-Aminothiazol-4-yl-LIGRL-NH(2) and 6-Aminonicotinyl-LIGRL-NH(2) Stimulate Multiple Signaling Pathways to Induce Physiological Responses in Vitro and in Vivo
Protease-activated receptor-2 (PAR(2)) is one of four protease-activated G-protein-coupled receptors. PAR(2) is expressed on multiple cell types where it contributes to cellular responses to endogenous and exogenous proteases. Proteolytic cleavage of PAR(2) reveals a tethered ligand that activates P...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2011
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3099721/ https://ncbi.nlm.nih.gov/pubmed/21467041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.185264 |
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